Human Growth Hormone

Human growth hormone (HGH) is produced naturally by the pituitary gland and secreted during sleep hours. IGF-1 and GH can be stimulated by the body, meaning that your natural levels can be increased, which gives you the ability to get most of the same results as a pro bodybuilder without the expense or risk. HGH steadily declines during aging from a high of 300-450 mg/mL as a young adult to as low as 30 mg/mL in the elderly. A minimum of HGH must be present in the body to maintain a healthy immune system and brain functioning. GH secretagogues (things that increase your natural production or secretion) are on the market and they should at least include things like ArgininePryoglutamate, Ornithine, Astragulus, and L-Dopa. HGH is present in cerebrospinal fluid and is able to cross the blood-brain barrier to reach receptor sites on the hypothalamus, pituitary, and hippocampus. The hippocampus controls a significant amount of cognitive functioning and memory.

Researchers have found low levels of HGH in several neurological disorders including Alzheimer's disease, Parkinson's disease, MS, and stroke. Formerly relegated to a position of minor importance by the scientific establishment, HGH has become the subject of intense scrutiny. Considerable research has been done on the effects of HGH over the past decade. Growth hormone deficiency in adults causes a variety of metabolic abnormalities including muscle mass loss, fat redistribution, abnormal lipid levels, abnormal cardiac function, decreased bone density, low energy and a reduced sense of well-being. In studies on middle aged and elderly people, HGH supplementation has increased muscle mass, skin thickness, and bone mass, while decreasing body fat. In patients with senile dementia and Alzheimer's disease, noticeable improvements have been observed with sustained use. Researchers theorize that HGH increases blood flow to the brain, regenerates neuronal dendrites and axons, and helps to rebuild protein that leads to the formation of RNA and DNA (Shippen et al. 1998).

An article in the journal Neurology described a study of the hormonal patterns in eight stroke patients and five matched healthy volunteers. The pulsatile nature of growth hormone secretion can result in undetectable serum concentrations between pulses making random measurement of growth hormone useless in diagnosis.Human Growth Hormone is a hormone produced by the pituitary gland in the brain. The pituitary gland is also responsible for the production of hormones like testosterone and estrogen. Nocturnal plasma hormone measurements showed low growth hormone levels and elevated prolactin concentrations. Cortisol levels, however, were normal. The authors concluded: "Suprahypothalmic lesions influence hypothalamus function so as to facilitate prolactin secretion and inhibit growth hormone release" .

Vinpocetine
Vinpocetine is derived from vincamine, the major indole alkaloid from the periwinkle plant. Vinpocetine has been used for many years in Europe to enhance memory and mental function. Vinpocetine improves blood supply to the brain, increases oxygen and glucose use by the brain, increases the vasodilation response to hypoxia (oxygen deficiency), and reduces abnormal coagulation of the blood.As the production of HGH slackens, our bodies have a harder time maintaining healthy cell growth. This reduction of HGH leads to signs of aging such as hair loss, brittle bones, loose and thinning skin, decreased mental function, decreased sexual performance, increase in body fat, and loss of lean muscle mass.

An article in the European Journal of Neurology described a study of 30 patients diagnosed with acute ischemic stroke. The National Institute of Health Stroke Scale was marginally (but significantly) better in the group treated with vinpocetine at 3 months. No significant adverse effects were seen. The authors concluded that a full-scale trial of vinpocetine was feasible and warranted